Published poster: “Mechanism-based Targeting of Sickle Cell Pathobiology and Pain with Novel Transdermal Curcumin”

Sickle Cell Disease (SCD) is a condition marked by acute and chronic pain, often accompanied by systemic complications such as inflammation, oxidative stress, and organ damage. Managing these symptoms remains a challenge due to limited bioavailability of conventional curcumin formulations. A breakthrough study presented by the American Society of Hematology highlights the potential of transdermal […]

FDA CBER & Vascarta Research Plan – Mechanistic insights into blood storage lesions and the development of antioxidant countermeasures

Vascarta’s groundbreaking research collaboration with Dr. Abdu Alayash of the FDA, formalized on December 1, 2022, marks a pivotal step in advancing therapeutic innovation. This partnership focuses on exploring the potential of Vascarta’s patented topical and transdermal curcumin technology for addressing critical conditions like sepsis and other inflammatory diseases. By combining Vascarta’s expertise in botanical […]

Novel Transdermal Curcumin Therapeutic Preserves Endothelial Barrier Function in a Rat Model of Sepsis.

Sepsis, a life-threatening inflammatory response to infection, continues to challenge healthcare with its complexity and high mortality rates. Preserving endothelial barrier function—a critical factor in vascular health—is key to managing this condition. A novel study investigates the potential of a transdermal curcumin therapeutic to protect endothelial integrity in a rat model of sepsis. Why Endothelial […]

Novel transdermal curcumin therapeutic preserves endothelial barrier function in a high-dose LPS rat model; ARTIFICIAL CELLS, NANOMEDICINE, AND BIOTECHNOLOGY 2023, VOL. 51, NO. 1, 33–40)

Curcumin, the active compound in turmeric, has long been hailed for its remarkable anti-inflammatory and therapeutic properties. Recent advancements in transdermal drug delivery technology are taking curcumin’s potential to new heights. A groundbreaking study explores how a novel transdermal curcumin gel preserves endothelial barrier function in a high-dose lipopolysaccharide (LPS) rat model. The endothelial barrier […]

Joel Friedman: Harnessing An Ancient Remedy Einstein Magazine Winter-Spring 2023

If you had wandered into Einstein’s Falk Center seven years ago, you might have overhead Joel Friedman, M.D., Ph.D.—a regular in the gym’s noontime pickup basketball games—extolling the virtues of curcumin, a derivative of the gold-colored herb turmeric. “I hadn’t been able to play basketball for several months because my knees hurt so much from […]